Article
Discerning an effective balance between equine infectious anemia virus attenuation and vaccine efficacy.
Journal of virology - 1 Mar 2005
Craigo Jodi K, Li Feng, Steckbeck Jonathan D, Durkin Shannon, Howe Laryssa, Cook Sheila J, Issel Charles, Montelaro Ronald C
Abstract excerpt
Among the diverse experimental vaccines evaluated in various animal lentivirus models, live attenuated vaccines have proven to be the most effective, thus providing an important model for examining critical immune correlates of protective vaccine immunity. We previously reported that an experimental live attenuated vaccine for equine infectious anemia virus (EIAV), based on mutation of the viral S2 accessory...
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