Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A unique evolution of the s2 gene of equine infectious anemia virus in hosts correlated with particular infection statuses.

Viruses - 10 Nov 2014

Wang Xue-Feng, Wang Shuai, Liu Qiang, Lin Yue-Zhi, Du Cheng, Tang Yan-Dong, Na Lei, Wang Xiaojun, Zhou Jian-Hua

Abstract excerpt

Equine infectious anemia virus (EIAV) is a member of the Lentivirus genus in the Retroviridae family that exhibits a genomic structure similar to that of HIV-1. The S2 accessory proteins play important roles in viral replication in vivo and in viral pathogenicity; however, studies on S2 evolution in vivo are limited. This study analyzed the evolutionary characteristics of the S2 gene of a pathogenic EIAV strain,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Evolution, Molecular
Share to Horses

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Infectious Anemia Virus, Equine

Share to RNA, Viral

Share to Selection, Genetic

Share to Sequence Homology, Amino Acid

Share to Time Factors

Share to Viral Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 25390683
DOI: 10.3390/v6114265
PMCID: PMC4246221

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A unique evolution of the s2 gene of equine infectious anemia virus in hosts correlated with particular infection statuses.PMID 25390683Read ↗

The S2 Gene of Equine Infectious Anemia Virus Is a Highly Conserved Determinant of Viral Replication and Virulence Properties in Experimentally Infected PoniesSemantic proximity Read ↗

Comparative analysis of LTR and structural genes in an equine infectious anemia virus strain isolated from a feral horse in Japan.Semantic proximity Read ↗

High Genomic Variability in Equine Infectious Anemia Virus Obtained from Naturally Infected Horses in Pantanal, Brazil: An Endemic Region Case.Semantic proximity Read ↗

Lessons in AIDS vaccine development learned from studies of equine infectious, anemia virus infection and immunity.Semantic proximity Read ↗

Reverse mutation of the virulence-associated S2 gene does not cause an attenuated equine infectious anemia virus strain to revert to pathogenicity.Semantic proximity Read ↗

A Live Attenuated Equine Infectious Anemia Virus Proviral Vaccine with a Modified <i>S2</i> Gene Provides Protection from Detectable Infection by Intravenous Virulent Virus Challenge of Experimentally Inoculated HorsesSemantic proximity Read ↗

Mutations occurring during serial passage of Japanese equine infectious anemia virus in primary horse macrophages.Semantic proximity Read ↗

S2 from equine infectious anemia virus is an infectivity factor which counteracts the retroviral inhibitors SERINC5 and SERINC3Semantic proximity Read ↗

The S2 gene of equine infectious anemia virus is dispensable for viral replication in vitro.Semantic proximity Read ↗

EIAV envelope diversity: shaping viral persistence and encumbering vaccine efficacy.Semantic proximity Read ↗

Deep sequencing and variant analysis of an Italian pathogenic field strain of equine infectious anaemia virus.Semantic proximity Read ↗

Adaptive immunity is the primary force driving selection of equine infectious anemia virus envelope SU variants during acute infection.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.