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Article

Influence of long terminal repeat and env on the virulence phenotype of equine infectious anemia virus.

Journal of virology - 1 Mar 2004

Payne Susan L, Pei Xiao-fang, Jia Bin, Fagerness Angela, Fuller Frederick J

Abstract excerpt

The molecular clones pSPeiav19 and p19/wenv17 of equine infectious anemia virus (EIAV) differ in env and long terminal repeats (LTRs) and produce viruses (EIAV(19) and EIAV(17), respectively) of dramatically different virulence phenotypes. These constructs were used to generate a series of chimeric clones to test the individual contributions of LTR, surface (SU), and transmembrane (TM)/Rev regions to the disease...

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Identifiers

PMID: 14963146
DOI: 10.1128/jvi.78.5.2478-2485.2004
PMCID: PMC369206

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