Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Zfp423 binds autoregulatory sites in p19 cell culture model.

PloS one - 1 Jan 2013

Cho Young-Wook, Hong Chen-Jei, Hou Aiju, Gent Peter M, Zhang Kuixing, Won Kyoung-Jae, Hamilton Bruce A

Abstract excerpt

Zfp423 is a 30 zinc finger transcription factor that forms regulatory complexes with EBF family members and factors targeted by canonical signaling pathways. Zfp423 mutations produce a range of developmental abnormalities in mice and humans related to the ciliopathies. Surprisingly, computational analysis of clustered Zfp423 and partner motifs in conserved genomic sequences predicts enrichment in Zfp423 and Ebf...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromatin Immunoprecipitation
Share to Enhancer Elements, Genetic

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Developmental

Share to Genes, Reporter

Share to Introns

Share to Luciferases

Share to Models, Biological

Share to Protein Isoforms

Source

Open in PubMed Open full text

Identifiers

PMID: 23762491
DOI: 10.1371/journal.pone.0066514
PMCID: PMC3675209

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Zfp423 binds autoregulatory sites in p19 cell culture model.PMID 23762491Read ↗

Zfp423 is required for normal cerebellar development.Semantic proximity Read ↗

Zeb2 DNA-binding sites in neuroprogenitor cells reveal autoregulation and affirm neurodevelopmental defects, including in Mowat-Wilson SyndromeSemantic proximity Read ↗

<i>Tulp3</i> quantitative alleles titrate requirements for viability, brain development, and kidney homeostasis but do not suppress <i>Zfp423</i> mutations in miceSemantic proximity Read ↗

<i>Zfp423</i> regulates Sonic hedgehog signaling via primary cilium functionSemantic proximity Read ↗

Multiple, distant Gata2 enhancers specify temporally and tissue-specific patterning in the developing urogenital system.Semantic proximity Read ↗

Zfp423 Regulates Sonic Hedgehog Signaling via Primary Cilium Function.Semantic proximity Read ↗

<i>Zfp423</i> , a Joubert syndrome gene, is a domain-specific regulator of cell cycle progression, DNA damage response and Purkinje cell development in the cerebellar primordiumSemantic proximity Read ↗

Dynamic site-specific recruitment of RBP2 by pocket protein p130 modulates H3K4 methylation on E2F-responsive promoters.Semantic proximity Read ↗

Disruption of SATB2 or its long-range cis-regulation by SOX9 causes a syndromic form of Pierre Robin sequence.Semantic proximity Read ↗

Analysis of FGF20-regulated genes in organ of Corti progenitors by translating ribosome affinity purification.Semantic proximity Read ↗

Strain-dependent modifier genes determine survival in <i>Zfp423</i> miceSemantic proximity Read ↗

Inactivation of a Novel FGF23 Regulator, FAM20C, Leads to Hypophosphatemic Rickets in MiceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.