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Article

Analysis of FGF20-regulated genes in organ of Corti progenitors by translating ribosome affinity purification.

Developmental dynamics : an official publication of the American Association of Anatomists - 1 Oct 2020

Yang Lu M, Stout Lisa, Rauchman Michael, Ornitz David M

Abstract excerpt

BACKGROUND: Understanding the mechanisms that regulate hair cell (HC) differentiation in the organ of Corti (OC) is essential to designing genetic therapies for hearing loss due to HC loss or damage. We have previously identified Fibroblast Growth Factor 20 (FGF20) as having a key role in HC and supporting cell differentiation in the mouse OC. To investigate the genetic landscape regulated by FGF20 signaling in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32492250
DOI: 10.1002/dvdy.211
PMCID: PMC7575056

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