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Article

Epigenetic aberrations in myeloid malignancies (Review).

International journal of molecular medicine - 1 Sept 2013

Takahashi Shinichiro

Abstract excerpt

The development of novel technologies, such as massively parallel DNA sequencing, has led to the identification of several novel recurrent gene mutations, such as DNA methyltransferase (Dnmt)3a, ten-eleven-translocation oncogene family member 2 (TET2), isocitrate dehydrogenase (IDH)1/2, additional sex comb-like 1 (ASXL1), enhancer of zeste homolog 2 (EZH2) and ubiquitously transcribed tetratricopeptide repeat X...

Topics

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Dioxygenases
DNA Methyltransferase 3A
Enhancer of Zeste Homolog 2 Protein
Gene Expression Regulation, Leukemic
Histone Demethylases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Leukemia, Myeloid

Polycomb Repressive Complex 2

Proto-Oncogenes

Source

Identifiers

PMID: 23760684
DOI: 10.3892/ijmm.2013.1417

Genes

ASXL1
TET2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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