Article
Different impact of IL10 haplotype on prognosis in lung squamous cell carcinoma and adenocarcinoma.
Anticancer research - 1 Jun 2013
Wang Yaw-Cheng, Sung Wen-Wei, Wang Lee, Cheng Ya-Wen, Chen Chih-Yi, Wu Tzu-Chin, Shieh Shwn-Huey, Lee Huei
Abstract excerpt
BACKGROUND: Polymorphisms (1082A>G, - 819C>T, and -592G>A) in the interleukin-10 (IL10) promoter are associated with its transcriptional activity. IL10 induction by cigarette smoking plays a role in smoking-related lung tumor progression. We therefore expected to find a difference in impact of IL...
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