Article
A ten-year clinical update of a large RET p.Gly533Cys kindred with medullary thyroid carcinoma emphasizes the need for an individualized assessment of affected relatives.
Clinical endocrinology - 1 Feb 2014
Signorini Priscila S, França Maria Inez C, Camacho Cleber P, Lindsey Susan C, Valente Flávia O F, Kasamatsu Teresa S, Machado Alberto L, Salim Camila P, Delcelo Rosana, Hoff Ana O, Cerutti Janete M, Dias-da-Silva Magnus R, Maciel Rui M B
Abstract excerpt
OBJECTIVE: Reviewing the clinical outcomes of a large kindred with a RET p.Gly533Cys mutation, 10 years after the first description of this kindred, has provided an important set of clinical data for healthcare decision-making. DESIGN AND PATIENTS: We identified 728 RET533 Brazilian relatives, sp...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.