Article
Multiple endocrine neoplasia type 2A due to an exon 8 (G533C) mutation in a large North American kindred.
Thyroid : official journal of the American Thyroid Association - 1 Dec 2013
Castro M Regina, Thomas Brittany C, Richards Melanie L, Zhang Jun, Morris John C
Abstract excerpt
BACKGROUND: Medullary thyroid cancer, although most commonly sporadic, may be part of the multiple endocrine neoplasia type 2 (MEN2) syndromes, generally due to mutations in the RET proto-oncogene. The majority of these mutations are located in exons 10, 11, and 13-16. More rarely, mutations in other exons have been described. We report for the first time a family from the United States with a rare mutation...
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