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Article

Genetic testing in medullary thyroid carcinoma syndromes: mutation types and clinical significance.

Mayo Clinic proceedings - 1 May 1997

Heshmati H M, Gharib H, Khosla S, Abu-Lebdeh H S, Lindor N M, Thibodeau S N

Abstract excerpt

OBJECTIVE: To determine the types of mutations and the clinical significance of a specific genotype in familial medullary thyroid carcinoma (MTC) syndromes. DESIGN: We retrospectively and prospectively studied patients with MTC at a tertiary referral center. MATERIAL AND METHODS: The study cohort consisted of 348 affected patients and at-risk family members of MTC kindreds, including 33 multiple endocrine...

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Identifiers

PMID: 9146685
DOI: 10.4065/72.5.430

Genes

RET

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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