Article
ERK signaling pathway regulates embryonic survival and eye development in goldfish, Carassius auratus.
Current molecular medicine - 1 Jul 2013
Li L, Wang L, Li T-T, Li X, Huang X-Q, Chen X-W, Li Z-L, Lv X-M, Liu F-Y, Luo Z-W, Liu M, Hu X-H, Hu W-F, Huang Z-X, Yi M, Liu S-J, Liu Y-Z, Li D W-C
Abstract excerpt
The extracellular signal-regulated kinase (ERK) is one of the three major types of mitogen-activated protein kinases. Previous studies showed that ERKs mediate various signaling pathways for cell proliferation, differentiation, survival and transformation in mammals. In the present study, we use goldfish as a model system and demonstrate that ERK kinases play important roles in promoting embryonic survival and...
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