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Article

Equarin is involved as an FGF signaling modulator in chick lens differentiation.

Developmental biology - 1 Aug 2012

Song Xiaohong, Sato Yuya, Felemban Athary, Ito Ayako, Hossain Mahmud, Ochiai Hiroshi, Yamamoto Takashi, Sekiguchi Kiyotoshi, Tanaka Hideaki, Ohta Kunimasa

Abstract excerpt

Lens growth involves the proliferation of epithelial cells, followed by their migration to the equator region and differentiation into secondary fiber cells. It is widely accepted that fibroblast growth factor (FGF) signaling is required for the differentiation of lens epithelial cells into crystallin-rich fibers, but this signaling is insufficient to induce full differentiation. To better understand lens...

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Identifiers

PMID: 22659080
DOI: 10.1016/j.ydbio.2012.05.029

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