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Article

α-Synuclein oligomers impair neuronal microtubule-kinesin interplay.

The Journal of biological chemistry - 26 Jul 2013

Prots Iryna, Veber Vanesa, Brey Stefanie, Campioni Silvia, Buder Katrin, Riek Roland, Böhm Konrad J, Winner Beate

Abstract excerpt

Early α-synuclein (α-Syn)-induced alterations are neurite pathologies resulting in Lewy neurites. α-Syn oligomers are a toxic species in synucleinopathies and are suspected to cause neuritic pathology. To investigate how α-Syn oligomers may be linked to aberrant neurite pathology, we modeled diff...

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Identifiers

PMID: 23744071
DOI: 10.1074/jbc.M113.451815
PMCID: PMC3724632

Genes

MAP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23744071-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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