Article
Association between neurotensin receptor 1 gene polymorphisms and alcohol dependence in a male Han Chinese population.
Journal of molecular neuroscience : MN - 1 Oct 2013
Ma Hui, Huang Yinglin, Zhang Bo, Wang Yuan, Zhao Hong, Du Hong, Cong Zhengtu, Li Jingying, Zhu Gang
Abstract excerpt
Neurotensin (NT) is a 13-amino acid multifunctional neuropeptide. Previous studies have demonstrated the roles of NT and its high-affinity receptor 1 (NTR1) in genetically mediated differential sensitivities to alcohol. However, no studies have investigated the association between NTR1 gene single-nucleotide polymorphisms (SNPs) and alcohol dependence (AD). We therefore examined this link. We genotyped three SNPs...
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