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Article

Effects of late gestational high-fat diet on body weight, metabolic regulation and adipokine expression in offspring.

International journal of obesity (2005) - 1 Nov 2013

Khalyfa A, Carreras A, Hakim F, Cunningham J M, Wang Y, Gozal D

Abstract excerpt

AIMS/HYPOTHESIS: Gestational exposures such as dietary changes can alter offspring phenotype through epigenetic modifications and promote increased risk for specific diseases, such as metabolic syndrome. We hypothesized that high-fat diet (HFD) during late gestation would lead increased risk for insulin resistance and hyperlipidemia via associated epigenetic alterations in tissue adipocytokine genes. METHODS:...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23399773
DOI: 10.1038/ijo.2013.12
PMCID: PMC3701742

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