Article
A novel method, the Variant Impact On Linkage Effect Test (VIOLET), leads to improved identification of causal variants in linkage regions.
European journal of human genetics : EJHG - 1 Feb 2014
Martin Lisa J, Ding Lili, Zhang Xue, Kissebah Ahmed H, Olivier Michael, Benson D Woodrow
Abstract excerpt
The Human Genome Project was expected to individualize medicine by rapidly advancing knowledge of common complex disease through discovery of disease-causing genetic variants. However, this has proved challenging. Although linkage analysis has identified replicated chromosomal regions, subsequent...
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