Article
CYP2C9 genotype and association with bone mineral density: a pilot study.
Gene - 10 Sept 2013
Brunner-Ziegler Sophie, Giurgea Georgiana-Aura, Sunder-Plassmann Raute, Hammer Alexandra, Margeta Christian, Brunner Martin, Koppensteiner Renate, Mannhalter Christine
Abstract excerpt
BACKGROUND: In recent years reduced bone mineral density (BMD) and osteoporosis have become major public health problems. Single nucleotide polymorphisms (SNPs) in the cytochrome P450 2C9 (CYP2C9) gene influence the response to oral anticoagulant drugs, which are positively associated with the risk to develop osteoporosis. The aim of the present investigation was to clarify a potential role of CYP2C9 sequence...
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