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Article

Heterozygosity for a coding SNP in COL1A2 confers a lower BMD and an increased stroke risk.

Biochemical and biophysical research communications - 10 Jul 2009

Lindahl Katarina, Rubin Carl-Johan, Brändström Helena, Karlsson Magnus K, Holmberg Anna, Ohlsson Claes, Mellström Dan, Orwoll Eric, Mallmin Hans, Kindmark Andreas, Ljunggren Osten

Abstract excerpt

Genetic variation plays an important role in osteoporosis and a prime candidate gene is Collagen alpha2(I) (COL1A2). A coding polymorphism (rs42524) in COL1A2 has previously been associated with intracranial aneurysms. Here the effects of this polymorphism have been studied in relation to bone mineral density (BMD) and prevalences of stroke and myocardial infarction (MI). rs42524 was genotyped in elderly men (n =...

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PMID: 19426706
DOI: 10.1016/j.bbrc.2009.05.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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