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Article

Abba is an essential TRIM/RBCC protein to maintain the integrity of sarcomeric cytoarchitecture.

Journal of cell science - 1 Aug 2013

Domsch Katrin, Ezzeddine Nader, Nguyen Hanh T

Abstract excerpt

Organized sarcomeric striations are an evolutionarily conserved hallmark of functional skeletal muscles. Here, we demonstrate that the Drosophila Abba protein, a member of the TRIM/RBCC superfamily, has a pivotal regulatory role in maintaining proper sarcomeric cytoarchitecture during development and muscle usage. abba mutant embryos initially form muscles, but F-actin and Myosin striations become progressively...

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Identifiers

PMID: 23729735
DOI: 10.1242/jcs.122366

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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