Article
Association between microRNA genetic variants and susceptibility to colorectal cancer in Chinese population.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Mar 2014
Hu Xuejiao, Li Lixin, Shang Mengqiao, Zhou Juan, Song Xingbo, Lu Xiaojun, Wang Jun, Ying Binwu, Wang Lanlan
Abstract excerpt
MicroRNAs (miRNAs) play an important role in the pathogenesis of neoplasm. Single nucleotide polymorphisms (SNPs) within miRNAs can change their phenotype and function. We attempted to analyze the relationship between two SNP loci in miRNAs and colorectal cancer (CRC) in Chinese Han population. We genotyped the polymorphism of two common miRNA SNPs, miR-146a (rs2910164 G > C) and miR-499 (rs3746444 T > C), in a...
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