Article
The association between four genetic variants in microRNAs (rs11614913, rs2910164, rs3746444, rs2292832) and cancer risk: evidence from published studies.
PloS one - 1 Jan 2012
He Bangshun, Pan Yuqin, Cho William C, Xu Yeqiong, Gu Ling, Nie Zhenglin, Chen Liping, Song Guoqi, Gao Tianyi, Li Rui, Wang Shukui
Abstract excerpt
MicroRNAs (miRNAs) participate in diverse biological pathways and may act as either tumor suppressor genes or oncogenes. Single nucleotide polymorphisms (SNPs) in miRNA may contribute to cancer development with changes in the microRNA's properties and/or maturation. Polymorphisms in miRNAs have been suggested in predisposition to cancer risk; however, accumulated studies have shown inconsistent conslusionss. To...
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