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Article

Environmental enrichment effects on the neurobehavioral profile of selective outbred trait anxiety rats.

Behavioural brain research - 1 Sept 2013

Ravenelle Rebecca, Byrnes Elizabeth M, Byrnes John J, McInnis Christine, Park Jin Ho, Donaldson S Tiffany

Abstract excerpt

Environmental enrichment attenuates the response to psychostimulants and has been shown to reduce both anxiety and stress-related behaviors. Since stress is a major vulnerability factor for addiction, we investigated whether enrichment could reverse stress profiles in high anxious rats as well as reduce their amphetamine sensitivity. Using selectively-bred high and low anxiety males (filial 3) from enriched,...

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Source

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Identifiers

PMID: 23727174
DOI: 10.1016/j.bbr.2013.05.041
PMCID: PMC4256945

Genes

AMPH
CORT
BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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