Article
Distinctive effects of unpredictable subchronic stress on memory, serum corticosterone and hippocampal BDNF levels in high and low exploratory mice.
Behavioural brain research - 17 Mar 2011
Kazlauckas Vanessa, Kalinine Eduardo, Leke Renata, Oses Jean Pierre, Nunes Fernanda, Espinosa Janaína, Mioranzza Sabrina, Lulhier Francisco, Portela Luis V, Porciúncula Lisiane O, Lara Diogo R
Abstract excerpt
Stress affects learning and memory processes and sensitivity to stress greatly varies between individuals. We studied behavioral and neurobiological effects of unpredictable subchronic stress (USCS) in two behavioral extremes of mice from the same strain (CF1) selected by their exploratory behavior of the central arena of an open field. The top and bottom 25% explorers were classified as low exploratory (LE) and...
Topics
- Analysis of Variance
- Animals
- Behavior, Animal
- Brain-Derived Neurotrophic Factor
- Corticosterone
- Enzyme-Linked Immunosorbent Assay
- Exploratory Behavior
- Hippocampus
- Male
- Memory
- Mice
- Phenotype