Article
Position of neocortical neurons transfected at different gestational ages with shRNA targeted against candidate dyslexia susceptibility genes.
PloS one - 1 Jan 2013
Adler William T, Platt Maryann P, Mehlhorn Alison J, Haight Joshua L, Currier Timothy A, Etchegaray Mikel A, Galaburda Albert M, Rosen Glenn D
Abstract excerpt
Developmental dyslexia is a language learning disorder that affects approximately 4-10% of the population. A number of candidate dyslexia susceptibility genes have been identified, including DCDC2 and KIAA0319 on Chromosome (Chr) 6p22.2 and DYX1C1 on Chr 15q21. Embryonic knockdown of the function of homologs of these genes in rat neocortical projection cell progenitors by in utero electroporation of plasmids...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
