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Article

Persistent damage induces mitochondrial DNA degradation.

DNA repair - 1 Jul 2013

Shokolenko Inna N, Wilson Glenn L, Alexeyev Mikhail F

Abstract excerpt

Considerable progress has been made recently toward understanding the processes of mitochondrial DNA (mtDNA) damage and repair. However, a paucity of information still exists regarding the physiological effects of persistent mtDNA damage. This is due, in part, to experimental difficulties associated with targeting mtDNA for damage, while sparing nuclear DNA. Here, we characterize two systems designed for targeted...

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Identifiers

PMID: 23721969
DOI: 10.1016/j.dnarep.2013.04.023
PMCID: PMC3683391

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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