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Article

Gene-centric association study of acute chest syndrome and painful crisis in sickle cell disease patients.

Blood - 18 Jul 2013

Galarneau Geneviève, Coady Sean, Garrett Melanie E, Jeffries Neal, Puggal Mona, Paltoo Dina, Soldano Karen, Guasch Antonio, Ashley-Koch Allison E, Telen Marilyn J, Kutlar Abdullah, Lettre Guillaume, Papanicolaou George J

Abstract excerpt

Patients with sickle cell disease (SCD) present with a wide range of clinical complications. Understanding this clinical heterogeneity offers the prospects to tailor the right treatments to the right patients and also guide the development of novel therapies. Several environmental (eg, nutrition) and nonenvironmental (eg, fetal hemoglobin levels, α-thalassemia status) factors are known to modify SCD severity. To...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23719301
DOI: 10.1182/blood-2013-01-478776
PMCID: PMC3716204

Genes

SCD
COMMD7

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