Article
Characterization of the relationship between APOBEC3B deletion and ACE Alu insertion.
PloS one - 1 Jan 2013
Wang Kang, Li Yuanyuan, Dai Chunyan, Wang Kaishi, Yu Jinghua, Tan Yiran, Zhang Wenyan, Yu Xiao-Fang
Abstract excerpt
The insertion/deletion (I/D) polymorphism of the angiotensin converting enzyme (ACE), commonly associated with many diseases, is believed to have affected human adaptation to environmental changes during the out-of-Africa expansion. APOBEC3B (A3B), a member of the cytidine deaminase family APOBEC3s, also exhibits a variable gene insertion/deletion polymorphism across world populations. Using data available from...
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