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Article

Association between dopamine D4 receptor polymorphism and age related changes in brain glucose metabolism.

PloS one - 1 Jan 2013

Volkow Nora D, Tomasi Dardo, Wang Gene-Jack, Telang Frank, Fowler Joanna S, Goldstein Rita Z, Klein Nelly, Wong Christopher, Swanson James M, Shumay Elena

Abstract excerpt

Aging is associated with reductions in brain glucose metabolism in some cortical and subcortical regions, but the rate of decrease varies significantly between individuals, likely reflecting genetic and environmental factors and their interactions. Here we test the hypothesis that the variant of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23717434
DOI: 10.1371/journal.pone.0063492
PMCID: PMC3661541

Genes

DRD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23717434-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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