Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cell-type, allelic, and genetic signatures in the human pancreatic beta cell transcriptome.

Genome research - 1 Sept 2013

Nica Alexandra C, Ongen Halit, Irminger Jean-Claude, Bosco Domenico, Berney Thierry, Antonarakis Stylianos E, Halban Philippe A, Dermitzakis Emmanouil T

Abstract excerpt

Elucidating the pathophysiology and molecular attributes of common disorders as well as developing targeted and effective treatments hinges on the study of the relevant cell type and tissues. Pancreatic beta cells within the islets of Langerhans are centrally involved in the pathogenesis of both type 1 and type 2 diabetes. Describing the differentiated state of the human beta cell has been hampered so far by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Gene Regulatory Networks

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Insulin-Secreting Cells

Share to Organ Specificity

Share to Quantitative Trait Loci

Share to Transcriptome

Source

Open in PubMed Open full text

Identifiers

PMID: 23716500
DOI: 10.1101/gr.150706.112
PMCID: PMC3759730

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cell-type, allelic, and genetic signatures in the human pancreatic beta cell transcriptome.PMID 23716500Read ↗

Single-Cell Transcriptome Profiling of Human Pancreatic Islets in Health and Type 2 DiabetesSemantic proximity Read ↗

Lessons from single-cell RNA sequencing of human isletsSemantic proximity Read ↗

Single-cell decoding of human islet cell type-specific alterations in type 2 diabetes reveals converging genetic- and state-driven β-cell gene expression defectsSemantic proximity Read ↗

An Integrated Map of Cell Type–Specific Gene Expression in Pancreatic IsletsSemantic proximity Read ↗

Aging of human endocrine pancreatic cell types is heterogeneous and sex-specificSemantic proximity Read ↗

Regulation of endocrine cell alternative splicing revealed by single-cell RNA sequencing in type 2 diabetes pathogenesisSemantic proximity Read ↗

Detailed transcriptome atlas of the pancreatic beta cellSemantic proximity Read ↗

PanKbase Integrated Single-Cell Map: A Comprehensive Atlas of Human Pancreatic IsletsSemantic proximity Read ↗

A transcriptional cross species map of pancreatic islet cellsSemantic proximity Read ↗

Single cell multiome profiling of pancreatic islets reveals physiological changes in cell type-specific regulation associated with diabetes riskSemantic proximity Read ↗

RNA Sequencing of Single Human Islet Cells Reveals Type 2 Diabetes GenesSemantic proximity Read ↗

Pancreas patch-seq links physiologic dysfunction in diabetes to single-cell transcriptomic phenotypesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.