Article
[Influence of CYP3A4/5 polymorphisms in the pharmacokinetics of levonorgestrel: a pilot study].
Biomedica : revista del Instituto Nacional de Salud - 1 Jan 2000
Moreno Iván, Quiñones Luis, Catalán Johanna, Miranda Carla, Roco Ángela, Sasso Jaime, Tamayo Evelyn, Cáceres Dante, Tchernitchin Andrei N, Gaete Leonardo, Saavedra Iván
Abstract excerpt
INTRODUCTION: Levonorgestrel a synthetic progestagen used for endometriosis, dysmenorrhea and emergency contraception, is quickly and completely absorbed in the digestive tract. levonorgestrel is predominantly metabolised through hepatic routes that utilise the CYP3A system (CYP3A4 and CYP3A5). O...
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