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Article

Molecular interactions in interleukin and toll-like receptor signaling pathways.

Current pharmaceutical design - 1 Jan 2014

Snyder Greg A, Sundberg Eric J

Abstract excerpt

The ability of a single protein fold to make multi-modal interactions with itself and others for transmitting biological signals across multiple receptor families is a recurring theme in signal transduction. The Toll/IL-1 receptor (TIR) domain represents an evolutionarily conserved alpha-beta Flavodoxin-like protein fold, which has evolved complex multifaceted molecular interactions capable of transmitting a...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23713776
DOI: 10.2174/13816128113199990069

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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