ERCC2 gene single-nucleotide polymorphism as a prognostic factor for locally advanced head and neck carcinomas after definitive cisplatin-based radiochemotherapy.

doi:10.1038/s41397-020-0174-1

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Article

ERCC2 gene single-nucleotide polymorphism as a prognostic factor for locally advanced head and neck carcinomas after definitive cisplatin-based radiochemotherapy.

The pharmacogenomics journal - 1 Feb 2021

Guberina Maja, Sak Ali, Pöttgen Christoph, Tinhofer-Keilholz Ingeborg, Budach Volker, Balermpas Panagiotis, Von der Grün Jens, Rödel Claus Michael, Gkika Eleni, Grosu Anca-Ligia, Abdollahi Amir, Debus Jürgen, Belka Claus, Pigorsch Steffi, Combs Stephani E, Mönnich David, Zips Daniel, De-Colle Chiara, Welz Stefan, Linge Annett, Lohaus Fabian, Baretton Gustavo, Gauler Thomas, Baumann Michael, Krause Mechthild, Schuler Martin, Bankfalvi Agnes, Höing Benedikt, Lang Stephan, Stuschke Martin

Abstract excerpt

Identifying patients with locally advanced head and neck carcinoma on high risk of recurrence after definitive concurrent radiochemotherapy is of key importance for the selection for consolidation therapy and for individualized treatment intensification. In this multicenter study we analyzed recurrence-associated single-nucleotide polymorphisms (SNPs) in DNA repair genes in tumor DNA from 132 patients with...

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PMID: 32546699
DOI: 10.1038/s41397-020-0174-1
PMCID: PMC7840506

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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