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Article

Significance of rs1271572 in the estrogen receptor beta gene promoter and its correlation with breast cancer in a southwestern Chinese population.

Journal of biomedical science - 28 May 2013

Chen Li, Liang Yan, Qiu Juhui, Zhang Lingling, Chen Xianchun, Luo Xiangdong, Jiang Jun

Abstract excerpt

BACKGROUND: To characterize single nucleotide polymorphisms (SNPs) within the promoter region of the estrogen receptor beta (ERβ) gene and to analyze the association of ERβ SNPs with susceptibility to breast cancer. Genotype frequencies of five SNPs (rs3020449, rs3020450, rs2987983, rs1271572 and rs1887994) in the promoter region of the ERβ gene in 873 women with breast cancer, 645 women with fibroadenoma and 700...

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Identifiers

PMID: 23711151
DOI: 10.1186/1423-0127-20-32
PMCID: PMC3672062

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