Article
Association of breast cancer risk with a GT dinucleotide repeat polymorphism upstream of the estrogen receptor-alpha gene.
Cancer research - 15 Sept 2003
Cai Qiuyin, Gao Yu-Tang, Wen Wanqing, Shu Xiao-Ou, Jin Fan, Smith Jeffrey R, Zheng Wei
Abstract excerpt
Recent studies suggest that genetic polymorphisms of the estrogen receptor-alpha (ER-alpha) gene may be associated with breast cancer risk. To evaluate the role of this gene in the risk of breast cancer, we genotyped a newly identified GT dinucleotide repeat [(GT)(n)] polymorphism located in the promoter region (6.6 kb upstream of the transcription start site) in 947 breast cancer cases and 993 age...
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