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Article

Protein tyrosine phosphatase variants in human hereditary disorders and disease susceptibilities.

Biochimica et biophysica acta - 1 Oct 2013

Hendriks Wiljan J A J, Pulido Rafael

Abstract excerpt

Reversible tyrosine phosphorylation of proteins is a key regulatory mechanism to steer normal development and physiological functioning of multicellular organisms. Phosphotyrosine dephosphorylation is exerted by members of the super-family of protein tyrosine phosphatase (PTP) enzymes and many play such essential roles that a wide variety of hereditary disorders and disease susceptibilities in man are caused by...

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PMID: 23707412
DOI: 10.1016/j.bbadis.2013.05.022

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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