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Article

Environment Changes Genetic Effects on Respiratory Conditions and Allergic Phenotypes.

Scientific reports - 24 Jul 2017

Song Yong, Schwager Michelle J, Backer Vibeke, Guo Jing, Porsbjerg Celeste, Khoo Siew-Kim, Laing Ingrid A, Moses Eric K, LeSouëf Peter, Zhang Guicheng Brad

Abstract excerpt

The prevalence of asthma and allergic diseases is disproportionately distributed among different populations, with an increasing trend observed in Western countries. Here we investigated how the environment affected genotype-phenotype association in a genetically homogeneous, but geographically separated population. We evaluated 18 single nucleotide polymorphisms (SNPs) corresponding to 8 genes (ADAM33, ALOX5,...

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Source

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Identifiers

PMID: 28740106
DOI: 10.1038/s41598-017-06791-y
PMCID: PMC5524954

Genes

ORMDL3
ADAM33
ALOX5
NOS1
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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