Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Animal models of disc degeneration and major genetic strategies.

Pain physician - 1 Jan 2000

Sun Fu, Qu Ji-Ning, Zhang Yin-Gang

Abstract excerpt

The establishment of a reliable animal model of lumbar disc degeneration (AMDD) is important for studying pathogenesis and evaluating treatment effectiveness. However, an ideal AMDD for use in laboratory studies has not yet been produced. This retrospective study reviews and compares several common AMDD and discusses their strengths and weaknesses. We also suggest a new method for establishing future AMDD. The...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animals, Genetically Modified
Share to Cytokines
Share to Disease Models, Animal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Extracellular Matrix Proteins

Share to Genetic Predisposition to Disease

Share to Genetic Therapy

Share to Intervertebral Disc Degeneration

Share to Receptors, Calcitriol

Source

Identifiers

PMID: 23703425

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Animal models of disc degeneration and major genetic strategies.PMID 23703425Read ↗

Genetics of lumbar disk degeneration: technology, study designs, and risk factors.Semantic proximity Read ↗

Protocol for disease-oriented Russian disc degeneration study (RuDDS) biobank facilitating functional omics studies of lumbar disc degenerationSemantic proximity Read ↗

Genetics of disc degeneration.Semantic proximity Read ↗

Lumbar disc degeneration: epidemiology and genetics.Semantic proximity Read ↗

In vivo Mouse Intervertebral Disc Degeneration Models and Their Utility as Translational Models of Clinical Discogenic Back Pain: A Comparative ReviewSemantic proximity Read ↗

Genetic Alterations in Intervertebral Disc DiseaseSemantic proximity Read ↗

Comparison of inbred mouse strains shows diverse phenotypic outcomes of intervertebral disc aging.Semantic proximity Read ↗

Lumbar disc degeneration: epidemiology and genetic influences.Semantic proximity Read ↗

Genetic animal models for retinal degeneration.Semantic proximity Read ↗

Genetic association studies in lumbar disc degeneration: a systematic review.Semantic proximity Read ↗

Genetics of the degenerated intervertebral disc.Semantic proximity Read ↗

Genetic risk factors for lumbar disc disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.