Article
Genetics of lumbar disk degeneration: technology, study designs, and risk factors.
The Orthopedic clinics of North America - 1 Oct 2011
Kao Patrick Yu-Ping, Chan Danny, Samartzis Dino, Sham Pak Chung, Song You-Qiang
Abstract excerpt
Lumbar disk degeneration (LDD) is a common musculoskeletal condition. Genetic risk factors have been suggested to play a major role in its cause. This article reviews the main research strategies that have been used to study the genetics of LDD, and the genes that thus far have been identified to influence susceptibility to LDD. With the rapid progress in genomic technologies, further advances in the genetics of...
Topics
- Age Factors
- Cross-Sectional Studies
- Disease Progression
- Female
- Genetic Predisposition to Disease
- Genetic Testing
- Genomics
- Humans
- Intervertebral Disc Degeneration
- Low Back Pain
- Lumbar Vertebrae