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Article

Dkk3, downregulated in cervical cancer, functions as a negative regulator of beta-catenin.

International journal of cancer - 15 Jan 2009

Lee Eun-Ju, Jo Minwha, Rho Seung Bae, Park Kyoungsook, Yoo Yae-Na, Park Junsoo, Chae Myounghee, Zhang Wei, Lee Je-Ho

Abstract excerpt

The Wnt/beta-catenin signaling pathway is activated during the malignant transformation of keratinocytes that originate from the human uterine cervix. Dkk1, 2 and 4 have been shown to modulate the Wnt-induced stabilization of the beta-catenin signaling pathway. However, the function of Dkk3 in th...

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Identifiers

PMID: 19003969
DOI: 10.1002/ijc.23913

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19003969-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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