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CHD4 in the DNA-damage response and cell cycle progression: not so NuRDy now

23 May 2013

Abstract excerpt

The CHD4 (chromodomain-helicase-DNA-binding 4) (or Mi-2β) protein is a founding component of the NuRD (nucleosome remodelling and deacetylation) complex. NuRD has long been known to function in transcriptional regulation, and is conserved throughout the animal and plant kingdoms. In recent years, evidence has steadily accumulated indicating that CHD4 can both function outside of the NuRD complex and also play...

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PMID: 23697937
DOI: 10.1042/bst20130027

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