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Article

Lineage Relationship of Gleason Patterns in Gleason Score 7 Prostate Cancer

22 May 2013

Abstract excerpt

Gleason score 7 (GS7) prostate cancer [tumors with both Gleason patterns 3 (GP3) and 4 (GP4)] portends a significantly more aggressive tumor than Gleason score 6 (GS6). It is, therefore, critical to understand the molecular relationship of adjacent GP3 and GP4 tumor cell populations and relate molecular abnormalities to disease progression. To decipher molecular relatedness, we used laser capture microdissection...

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Identifiers

PMID: 23695551
DOI: 10.1158/0008-5472.can-12-2803

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