Article
Analysis of atherosclerosis susceptibility in mice with genetic defects in platelet function.
Arteriosclerosis (Dallas, Tex.) - 1 Jan 2000
Paigen B, Holmes P A, Novak E K, Swank R T
Abstract excerpt
To determine whether platelets contribute to the development of atherosclerosis, we compared the severity of atherosclerosis in susceptible C57BL/6 mice carrying either a normal or a variant phenotype for platelet function. Five genetically distinct mutants with increased bleeding times and abnor...
Topics
- Animals
- Arteriosclerosis
- Blood Platelets
- Disease Models, Animal
- Disease Susceptibility
- Female
- Mice
- Mice, Inbred C57BL
- Mice, Mutant Strains
- Mutation
- Serotonin