Article
Modulation of behavioral and neurochemical responses of adult zebrafish by fluoxetine, eicosapentaenoic acid and lipopolysaccharide in the prolonged chronic unpredictable stress model.
Scientific reports - 12 Jul 2021
Demin Konstantin A, Kolesnikova Tatiana O, Galstyan David S, Krotova Nataliya A, Ilyin Nikita P, Derzhavina Ksenia A, Levchenko Nataliia A, Strekalova Tatyana, de Abreu Murilo S, Petersen Elena V, Seredinskaya Maria, Cherneyko Yulia V, Kositsyn Yuriy M, Sorokin Dmitry V, Zabegalov Konstantin N, Mor Mikael S, Efimova Evgeniya V, Kalueff Allan V
Abstract excerpt
Long-term recurrent stress is a common cause of neuropsychiatric disorders. Animal models are widely used to study the pathogenesis of stress-related psychiatric disorders. The zebrafish (Danio rerio) is emerging as a powerful tool to study chronic stress and its mechanisms. Here, we developed a prolonged 11-week chronic unpredictable stress (PCUS) model in zebrafish to more fully mimic chronic stress in human...
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