Article
Epidemiology of isoniazid resistance mutations and their effect on tuberculosis treatment outcomes.
Antimicrobial agents and chemotherapy - 1 Aug 2013
Huyen Mai N T, Cobelens Frank G J, Buu Tran N, Lan Nguyen T N, Dung Nguyen H, Kremer Kristin, Tiemersma Edine W, van Soolingen Dick
Abstract excerpt
Isoniazid resistance is highly prevalent in Vietnam. We investigated the molecular and epidemiological characteristics and the association with first-line treatment outcomes of the main isoniazid resistance mutations in Mycobacterium tuberculosis in codon 315 of the katG and in the promoter regio...
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