Article
Comparative proteomics and correlated signaling network of kidney in ApoE deficient mouse.
Proteomics. Clinical applications - 1 Dec 2013
Lv Xiaoyan, Ai Jianzhong, Li Mi, Wang Honglian, Chen Tielin, Fang Yin, Liu Yunhong, Zhou Puhui, Chen Mianzhi, Tan Ruizhi, Liu Yuhang, Yang Yang, Zhou Qin
Abstract excerpt
PURPOSE: Apolipoprotein E knockout (apoE-/- ) mouse is one of the most popular models for cardiovascular research, especially in the study of atherosclerosis. Naturally, large amount of studies try to uncover the role of apoE in atherosclerosis, and indeed apoE plays an important role in this pathogenesis. Kidney is an organ that contains lots of capillaries and also largely expresses apoE. Moreover, a protective...
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