Article

Lipoprotein glomerulopathy induced by ApoE Kyoto mutation in ApoE-deficient mice

2020-10-09

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Lipoprotein glomerulopathy (LPG) is a rare autosomal dominant kidney disease that is most commonly caused by mutations in ApoE Kyoto (p.R43C) and ApoE Sendai (p.R163P). Differences in phenotype among the various ApoE mutations have been suggested, but the pathogenic role of ApoE Kyoto has not been validated in an animal model. This study intended to establish an...

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Literature Corpus work: 52ba37eb-1d1b-54e1-8124-da103a398b36
DOI: 10.21203/rs.3.rs-87559/v1

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