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Article

Lipoprotein glomerulopathy induced by ApoE-Sendai is different from glomerular lesions in aged apoE-deficient mice.

Clinical and experimental nephrology - 1 Oct 2009

Ishimura Atsunori, Watanabe Maho, Nakashima Hitoshi, Ito Kenji, Miyake Katsuhisa, Mochizuki Shizue, Ishigaki Yasushi, Saito Takao

Abstract excerpt

OBJECTIVE: A mutant of apolipoproteinE (apoE), ApoE-Sendai (Arg145Pro), is one of the major causative factors of human lipoprotein glomerulopathy (LPG). An apoE-deficient mouse with introduced ApoE-Sendai gene (ApoE-Sendai mouse) developed a murine counterpart of LPG, whereas it was also reported that apoE-deficient mouse (apoE KO mouse) spontaneously developed LPG-like lesion regardless of introduction of...

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PMID: 19459027
DOI: 10.1007/s10157-009-0195-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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