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Article

IL-4 and MTHFR gene polymorphism in rheumatoid arthritis and their effects.

Immunology letters - 1 May 2013

Inanir Ahmet, Yigit Serbulent, Tekcan Akın, Tural Sengul, Kismali Gorkem

Abstract excerpt

Rheumatoid arthritis (RA) is a chronic, systemic inflammatory disease that mainly affects the joints. Polymorphic variations of the cytokine genes and MTHFR gene have received attention as potential markers of susceptibility, severity, and/or protection in RA. The aim of this study was to investigate the MTHFR C677T and IL-4 70bp VNTR variation in Turkish patients with RA and evaluate if there was an association...

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Source

Identifiers

PMID: 23685257
DOI: 10.1016/j.imlet.2013.05.004

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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