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Article

Young little mice express a premature cardiovascular aging phenotype.

The journals of gerontology. Series A, Biological sciences and medical sciences - 1 Feb 2014

Reddy Anilkumar K, Hartley Craig J, Pham Thuy T, Darlington Gretchen, Entman Mark L, Taffet George E

Abstract excerpt

To investigate the effect of growth hormone and insulin-like growth factor 1 deficiency on the aging mouse arterial system, we compared the hemodynamics in young (4 months) and old (30 months) growth hormone-releasing hormone receptor null dwarf (Little) mice and their wild-type littermates. Youn...

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Identifiers

PMID: 23682160
DOI: 10.1093/gerona/glt055
PMCID: PMC4038241

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23682160-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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