Article
Effects of thymus irradiation on the immune competence of T cells after total-lymphoid irradiation.
Transplantation - 1 Jul 1990
Palathumpat V C, Vandeputte M M, Waer M
Abstract excerpt
Spleen cells from mice receiving TLI, with or without thymus shielding, were investigated for in vitro and in vivo defects. At 4-6 weeks after irradiation spleen cells of both groups showed a normal number of Thy1 (T cells), L3T4 (CD4 positive T cells) cells, and an absence of natural suppressor cells. Splenocytes of the nonthymic shielded TLI group were not able to mount either a normal in vitro response (in MLR...
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